Nathalia Magalhães
- Postdoc, Antunes Lab
Contact Info
Biography —
Hometown: Rio de Janeiro, Brazil
Education —
Research —
During my MSc and Ph.D. degrees, I focused on mechanisms associated with HPA axis hyperactivity in diabetic animals. One of the most significant components I found was the participation of gut microbiota in this phenomenon. Since then, I have loved to know how gut microbiota can be involved in several responses of hosts against different situations. Presently, I analyze molecules produced by members of the gut microbiota and how these molecules can act in the infection of intestinal pathogens such as Salmonella sp. and Vibrio sp. Among the objectives established by this project, we seek to understand how these molecules act on virulence factors of the bacteria and their effect on the host's immune cells.
Selected Publications —
Chaves AS, Magalhães NS, Insuela DBR, Silva PMRE, Martins MA and Carvalho VF (2022) Effect of the renin-angiotensin system on the exacerbation of adrenal glucocorticoid steroidogenesis in diabetic mice: Role of angiotensin-II type 2 receptor. Front. Endocrinol. 13:1040040.
Magalhães NS, Savino W; Silva PMR, Martins MA, Carvalho VF. Gut Microbiota Dysbiosis Is a Crucial Player for the Poor Outcomes for COVID-19 in Elderly, Diabetic, and Hypertensive Patients. 2021. Frontiers in Medicine, v. 8, p. 644751.
Raíssa D. Ventura, Amanda S. Chaves, Nathalia S. Magalhães, Florencia B. Gonzalez, Maria Florencia Pacini, Ana Rosa Pérez, Patrícia M.R. Silva, Marco A. Martins, Vinicius F. Carvalho, Activation of PPARγ reduces N-acetyl-cysteine -induced hypercorticoidism by down-regulating MC2R expression into adrenal glands, Free Radical Biology and Medicine, V156, 2020,137-143.
Rafael Carvalho Torres, Nathalia Santos Magalhães, Patrícia M.R. e Silva, Marco A. Martins, Vinicius F. Carvalho. Activation of PPAR-γ reduces HPA axis activity in diabetic rats by up-regulating PI3K expression, Experimental and Molecular Pathology, V101, 2016.