Brian Ackley receives a 2022 J.R. and Inez Jay Fund research award

Brian Ackley (associate professor) received a 2022 J.R. and Inez Jay Fund research award for his proposal titled “Ultrastructural Analysis of Synaptic Degeneration in Rapidly Developing AD Models.” The project aims to study the formation of protein aggregates in neurons that can lead to a progressive loss of synapses during aging. The study may lead to a better understanding of the origin and causes of early-stage Alzheimer’s disease and provide ways to treat or prevent the disease and other neurodegenerative disorders. Ackley will collaborate on the project with Michael Wolfe (Mathias P. Mertes Professor of Medicinal Chemistry), and consult with David Hall, (Professor of neuroscience at the Albert Einstein College of Medicine), and Matthew Buechner (program director of the Cellular Dynamics & Function Cluster Biology Directorate at the National Science Foundation).