Cancer Biology
Our scientific goal is to understand the molecular mechanisms that define normal and neoplastic cell growth in order to identify and characterize molecules, pathways and processes that are involved in tumor development, growth and progression. We are unified by utilization of molecular, biochemical, genetic, and cell-based approaches to study the underlying biology, molecular biology and biochemistry of tumor cells and their surrounding microenvironments. Collaborative, interdisciplinary, discovery-oriented basic cancer research will identify new targets that can be used for prognostic and therapeutic objectives.
Select a faculty member from the list below to learn more about their research in this area:
The function of Ewing sarcoma proteins in mitosis.
The role of posttranslational modification by SUMO on cell division cycle.
T cell activation, cell signaling, adhesion molecules.
Developmental neurobiology, genetics, and genomics.
Role of APC tumor suppressor protein in normal colon and in cancer.
Exploring membrane protein folding through protein design, bioinformatics, and molecular biology.
Structure and function of key biomacromolecules.
ABC transporters and RNAi: anti-foreign genome responses and stem cell regulation.
Molecular therapy targeting cancer and cancer stem cells, via novel nanovectors and rational drug design.
