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September 2015 News

David Davido (associate professor) co-chaired the graduate student and post-doctoral trainee presentation session at the Colorado Alphaherpesvirus Latency Symposium in Vail, CO, May 14-16 and will continue to serve on the planning committee for the 2016 meeting.  David also served as a moderator for the Gene Expression/ Signaling Session at the 40th International Herpesvirus Workshop in Boise, ID, from July 25-29.



John Karanicolas (associate professor) is the recipient of a Kansas IDeA Network of Biomedical Research Excellence (K-INBRE) Bridging Grant for his project entitled “Identifying stabilizers of p53 using pocket complementarity.”  This project is aimed identifying compounds that “re-activate” the tumor suppressor p53, and can thus serve as a starting point for developing new broad-spectrum cancer therapeutics.



Chris Gamblin (professor) was an Organizing Committee Member and Session Chair for the first annual International Conference on Brain Disorders and Therapeutics held August 24-26th in London, England. He also gave a plenary presentation entitled “Mining the A. nidulans Metabolome for Tau aggregation inhibitors.”




Angela Fowler (graduate student, Davido lab) participated in the Chemistry-Biology Interface Career Development Workshop at Vanderbilt University, August 10-12.  Angela was one of six graduate students chosen to be the KU delegation, which also included students from chemistry, medicinal chemistry and pharmaceutical chemistry.  Audrey Lamb (professor) and Tom Prisinzano (professor and chair, medicinal chemistry) served as mentors at the conference.



Christian Gomez (graduate student, Neufeld lab) was the recipient of a travel award from the Federation of American Societies for Experimental Biology (FASEB) to help defray expenses associated with attending the Gastrointestinal Tract XVI: GI Homeostasis, the Microbiome and the Barrier, Development and Disease FASEB Science Research Conference.  At the Conference, held August 2-7 in Steamboat Springs, CO, Gomez presented a poster entitled “A Role for Tumor Suppressor APC in Goblet Cells and Inflammation.”


Nikola Kenjic (graduate student, Lamb lab) is the recipient of a Graduate Scholarly Presentation Travel Fund Award to attend the Midwest Enzyme Chemistry Conference in Chicago, IL on September 12.  Nikola will present a poster entitled “PvdF as potential novel transformylase from Pseudomonas aeruginosa.”





Smita Paranjape (doctoral graduate, Gamblin lab) has accepted a postdoctoral research position in the laboratory of Dr. Mark Zylka in the department of Cell Biology and Physiology at the University of North Carolina School of Medicine where she will be studying the underlying causes of Autism Spectrum Disorders.




Lauren Arney and Dharam Patel (undergraduates, Lamb lab) are recipients of KU Center for Undergraduate Research Travel Awards to attend the Midwest Enzyme Chemistry Conference in Chicago, IL on September 12.  Lauren will present a poster entitled “Allosteric regulation in pyruvate kinase” and Dharam will present a poster entitled “The production, purification and post-translational modification of PvdJ module 2 in Pseudomonas aeruginosa.”


Michael Cory (undergraduate, Karanicolas lab) and Aidan Dmitriev (undergraduate, Hefty lab) were named as the inaugural Beckman Scholars, a 15 month program to conduct innovative mentored research here at KU.  Michael and Aiden receive research and travel stipends and supply funds to conduct their research projects.  Michael is studying protein-based switches and sensors in the Karanicolas lab, whereas Aidan is working to understand the disease processes of Chlamydia.  Read the article from KU Today.


Jessica van Loben Sels (undergraduate, Davido Lab) was the recipient of a KU Center for Undergraduate Research Travel Awards and an American Society of Virology Travel Scholarship to attend the American Society of Virology Meeting  in London, Canada, on July 11 - 15, where she presented a poster entitled "The N-terminus of the HSV-1 E3 Ubiquitin Ligase ICP0 Stimulates Viral Replication and Gene Expression in Cells Exposed to Interferon-β".  Jessica has been awarded a K-INBRE Star Trainee Fellowship and is the recipient of a prestigious, national Astronaut Scholarship.

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September 2015 Presentations

Susan Egan (professor) gave an oral presentation entitled “Allosteric Rhamnose Signaling in the E. coli AraC Family Protein RhaR” at the Molecular Genetics of Bacteria and Phages Meeting in Madison, WI, on August 5.

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September 2015 Publications

Barta ML, Battaile KP, Lovell S, Hefty PSHypothetical Protein CT398 (CdsZ) Interacts with σ54 (RpoN)-Holoenzyme and the Type III Secretion Export Apparatus in Chlamydia trachomatis.  Protein Sci [Epub ahead of print]

Gonzalez C, Ray JCJ, Manhard M, Adams RM, Nevozhay D, Morozov AV, Balazsi G.  Stress-response balance drives the evolution of a network module and its host genomeMol Systems Biol 11: 827.

Oakley BR, Paolillo V, Zheng Y.  gamma-tubulin complexes in microtubule nucleation and beyondMol Biol Cell 26: 2957-2962.

Truong TT, Seyedsayamdost M, Greenberg EP, Chandler JRA Burkholderia thailandensis acyl-homoserine lactone-independent LuxR homolog that activates production of the cytotoxin malleilactoneJ. Bacteriol [Eub ahead of print]

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Molecular Biosciences

We are an interdisciplinary group of faculty who perform cutting edge research in a wide range of areas including biochemistry, biophysics, structural biology, bioinformatics, cancer biology, genetics, genomics, immunology, microbiology, virology, neurobiology, molecular, cellular and developmental biology.  We work closely with postdoctoral fellows, graduate students, and undergraduates to investigate fundamental biological problems on all levels from molecules to cells to organisms.  The Department of Molecular Biosciences, located on the Lawrence campus of the University of Kansas system, is an excellent environment for research and education.

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