February 2018 News   

Mizuki Azuma (associate professor) is the recipient of a National Cancer Institute Small Grant Program (R03) award for her proposal entitled "O-GlcNAcylation of Ewing sarcoma proteins in chromosomal maintenance." This is a multi-PI grant with Mizuki Azuma and Chad Slawson of KUMC.  The goal of this project is to understand DNA mutations in a rare form of childhood bone cancer (Ewing sarcoma) by looking at how the chromosomes change after a sugar is attached to proteins implicated in disease progression.

 

Christian Ray (assistant professor) was selected to organize a conference, Computation by Natural Systems at the UK Royal Society with co-organizers Dominique Chu (University of Kent,UK) and Mikhail Prokopenko (University of Sydney, Australia). The conference will be held in Kavli Royal Society Centre in Buckinghamshire, UK from March 21-22, 2018.

 

 

Vaughn Craddock (undergraduate, Chandler Lab) and Mary Mitchell (undergraduate, Macdonald Lab) were the recipients of K-INBRE undergraduate research fellowships for the Spring/Summer 2018. Vaughn’s project is entitled, “Quorum sensing control of antibiotic resistance in the pathogenic bacterium Pseudomonas aeruginosa." Mary’s project is entitled, "The Genetic Basis of Sleep Deprivation in Drosophila melanogaster."

 

 

Cara Davis (undergraduate, Lamb lab) was awarded first place for her podium presentation at the annual symposium of the Kansas IDeA Network of Biomedical Research Excellence in Overland Park, KS on January 13.  Cara’s talk was entitled, “Biosynthesis of yersinopine: an opine metallophore from Yersinia pestis.

 

 

Emily Freeburne (undergraduate, Timmons lab) has received a KU Undergraduate Research Award for Spring 2018 for her project: “Identification of Three Genes Required for RNAi in C. elegans.”

Emily Smith (undergraduate, Timmons lab) has received a KU Undergraduate Research Award for Spring 2018 for her project: “Dimerization Partners of Half Transporters.” 

 

               

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February 2018 Presentations

Josie Chandler (assistant professor) gave a talk entitled “Making friends to make war: bacterial quorum sensing, cooperation and competition” at the University of Missouri, Division of Biological Sciences on December 5, 2017.

Tom Hill (post doc, Unckless lab) gave a talk entitled “The constancy of transposable element dynamics across Drosophila species” at the Population Genetics group at the University of Bristol, UK on January 4, 2018. 

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February 2018 Publications

Evans KC, Benomar S, Camuy-Vélez LA, Nasseri EB, Wang X, Neuenswander B, Chandler JR.  Quorum-sensing control of antibiotic resistance stabilizes cooperation in Chromobacterium violaceum. The ISME J 2018 10.1038/s41396-018-0047-7.

Mostafa HH, Thompson TW, Konen AJ, Haenchen SD, Hilliard JG, Macdonald SJ, Morrison LA, Davido DJ. Herpes Simplex Virus 1 Mutant with Point Mutations in UL39 Is Impaired for Acute Viral Replication in Mice, Establishment of Latency, and Explant-Induced Reactivation.J Virol. 2018 Jan 10. pii: JVI.01654-17. doi: 10.1128/JVI.01654-17.​

Muralidharan R, Mehta M, Ahmed R, Roy S, Xu L, Aubé J, Chen A, Zhao YD, Herman T, Ramesh R, Munshi A. HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells. Scientific Reports 2017; 7:9694.

Ni Z, He J, Wu Y, Hu C, Dai X, Yan X, Li B, Li X, Xiong H, Li Y, Li S, Xu L, Li Y, Lian J, He F. AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells. Autophagy [Epub ahead of print].

Dohn, J, Grubbs A, Oakley E,  Oakley B. New multi-marker strains and complementing genes for Aspergillus nidulans molecular biology. Fungal Genetics and Biology [Epub ahead of print].

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Molecular Biosciences

We are an interdisciplinary group of faculty who perform cutting edge research in a wide range of areas including biochemistry, biophysics, structural biology, bioinformatics, cancer biology, genetics, genomics, immunology, microbiology, virology, neurobiology, molecular, cellular and developmental biology.  We work closely with postdoctoral fellows, graduate students, and undergraduates to investigate fundamental biological problems on all levels from molecules to cells to organisms.  The Department of Molecular Biosciences, located on the Lawrence campus of the University of Kansas system, is an excellent environment for research and education.

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