• Home
  • Kathy A. Suprenant

Kathy A. Suprenant

Emeritus Professor
Primary office:
Haworth Hall


The cytoskeleton in cell division, development and neuromuscular function.

The research of the Suprenant laboratory is focused on molecular mechanisms of microtubule-associated protein function. We combine studies of the basic biochemistry and molecular biology of microtubules and microtubule-associated proteins, high-resolution time-lapse microscopy of microtubule dynamics, and genetic analyses of protein function. 

Representative Publications
  • Cellular Curiosities: Intracellular Cathedrals (2013) http://www.cell.com/pictureshow/cell-curiosities
  • Hueston J.L., and Suprenant K.A. Loss of dystrophin and the microtubule-binding protein ELP-1 causes progressive paralysis and death of adult C. elegans. (2009) Dev Dyn. 238:1878 PubMed Central PMCID: PMC2942758.
  • Hueston, J.L., Herren, G.P., Cueva, J.G., Buechner, M.J., Lundquist, E.A., Goodman, M.B., and Suprenant, K.A. (2008) The C. elegans EMAP-like protein, ELP-1 is required for normal touch sensation and associates with microtubules and adhesion complexes. BMC Developmental Biology 8:110 (E-pub 17 November, 2008).
  • Dickensen, N., Moore, D., Suprenant, K., and Dunn, R.C. (2007) Vault Ribonucleoprotein Particles and the Nuclear Pore Complex. Photochem Photobiol. 83(3):686–91.
  • Suprenant, K.A., Bloom, N., Fang, J. and Lushington, G. (2007) The major vault protein is related to the toxic anion resistance protein (TelA) family. Journal of Experimental Biology.210:946–955.*†
    * Featured in Inside JEB section with an article entitled: “The Mystery of Vaults.”
    † Included in The Journal of Experimental Biology Highlights, published October 2007
  • Rodriguez, A.J., Seipel, S.A., Hamill, D.R., Romancino, D.R., Di Carlo, M., Suprenant, K.A. and Bonder, E.M. (2005): Seawi--a sea urchin piwi/argonaute family member is a component of MT-RNP complexes RNA 11:646–656.
  • Foland, T.B., Dentler, W.L., Suprenant, K.A., Gupta Jr., M., and Himes, R.H. (2005) Paclitaxel-induced microtubule stabilization causes mitotic block and apoptotic-like cell death in a paclitaxel-sensitive strain of Saccharomyces cerevisiae Yeast 22:971–978.
  • Stewart, P.L., Makabi, M., Lang, J., Dickey-Sims, C., Robertson, A.J., Coffman, J.A. and Suprenant, K.A. (2005): Sea urchin vault structure, composition, and differential localization during development. BMC Developmental Biology 5:3 (e-pub 14 Feb 2005).
  • Bode, C., Gupta, M.L., Suprenant, K.A. and Himes, R.H. (2003): The two a–tubulin isotypes in budding yeast have opposing effects on microtubule dynamics in vitro. EMBO Reports 4:94–99.
  • Eichenmüller, B., Kedersha, N., Solovyeva, E. Everley, P., Lang, J., Himes, R.H., and Suprenant, K.A. (2003): Vaults bind directly to microtubules via their caps and not their barrels. Cell Motility and the Cytoskeleton 56:225–236 (AND COVER).
  • Eichenmüller, B., Everley, P., Palange, J., Lepley, D., and Suprenant, K. A. (2002): The human EMAP-like protein-70 is a microtubule destabilizer that localizes to the mitotic apparatus. Journal of Biological Chemistry 277:1301–1309.
  • Suprenant, K.A. (2002): Vault ribonucleoprotein particles; sarcophagi, gondolas or safety deposit boxes? Biochemistry 41: 14447–14454.
  • Bode, C. J., Gupta, M.L., Reiff, E.A., Suprenant, K. A., Georg, G.I., and Himes, R.H. (2002): Epothilone and paclitaxel: unexpected differences in promoting the assembly and stabilization of yeast microtubules. Biochemistry 41: 3870–3874.
  • Gupta, M.L., Bode, C.J., Thrower, D.A., Suprenant, K.A., Bloom, K.S. and Himes, R.H. (2002): b-tubulin C354 mutations that severely decrease microtubule dynamics do not prevent nuclear migration in yeast Molecular Biology of the Cell 13(8): 2919–32.

Search PubMed for articles by Kathy A. Suprenant.


Home to 50+ departments, centers, and programs, the School of the Arts, and the School of Public Affairs and Administration
KU offers courses in 40 languages
No. 1 ranking in city management and urban policy —U.S. News and World Report
One of 34 U.S. public institutions in the prestigious Association of American Universities
44 nationally ranked graduate programs.
—U.S. News & World Report
Top 50 nationwide for size of library collection.
—ALA
23rd nationwide for service to veterans —"Best for Vets," Military Times
KU Today